ࡱ>  bjbj 4}+77777KKK8<K_fA(W(W(W(F)F)F)_______Mac:_7F)F)F)F)F)_77W(W(_+++F)7W(7W(_+F)_++jT ZW(ЁK*V2v__0_VJ)d+j)dd Z Z\)d7fZF)F)+F)F)F)F)F)__+F)F)F)_F)F)F)F))dF)F)F)F)F)F)F)F)F) :  In the News March 28 April 10, 2009 Drug- and Pharmacy-Related News Brought to You by the Pharmacy Library People Basic Sciences Research Yanaka A, Fahey JW, Fukumoto A et al. Dietary sulforaphane-rich broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori-infected mice and humans. HYPERLINK "http://cancerprevres.aacrjournals.org/cgi/content/abstract/2/4/353?view=long&pmid=19349290"Cancer Prev Res (Phila Pa). 2009 Apr;2(4):353-60. The following news story refers to the study following: Carey B. HYPERLINK "http://www.nytimes.com/2009/04/07/health/07itch.html?partner=rss&emc=rss"Scratching relieves itch by quieting nerve cells. New York Times. April 7, 2009. Davidson S, Zhang X, Khasabov SG et al. Relief of itch by scratching: State-dependent inhibition of primate spinothalamic tract neurons. HYPERLINK "http://www.nature.com/neuro/journal/vaop/ncurrent/abs/nn.2292.html"Nat Neurosci. 2009 Apr 6. [Epub ahead of print] Cardiology Harper M. HYPERLINK "http://www.forbes.com/2009/03/30/statins-heart-disease-business-healthcare-statins.html"ACC Conference: Statins dethroned.  Forbes.com. March 30, 2009. The following study and editorial commentary are related: Feldman RD, Zou GY, Vandervoort MK et al. A simplified approach to the treatment of uncomplicated hypertension: A cluster randomized, controlled trial. HYPERLINK "http://hyper.ahajournals.org/cgi/content/abstract/53/4/646"Hypertension. 2009 Apr;53(4):646-53. Epub 2009 Feb 23. Egan BM. Fixed-dose combinations and hypertension control in community-based practices: Application of the "keep-it-simple" principle. HYPERLINK "http://hyper.ahajournals.org/cgi/content/extract/hypertensionaha;53/4/598"Hypertension. 2009 Apr;53(4):598-9. Epub 2009 Feb 23. Steinke L, Lanfear DE, Dhanapal V, Kalus JS. Effect of "energy drink" consumption on hemodynamic and electrocardiographic parameters in healthy young adults. HYPERLINK "http://www.theannals.com/cgi/content/abstract/43/4/596"Ann Pharmacother. 2009 Apr;43(4):596-602. Epub 2009 Mar 18. Chopra V, Plaisance B, Cavusoglu E et al. Perioperative beta-blockers for major noncardiac surgery: Primum Non Nocere. HYPERLINK "http://www.amjmed.com/article/S0002-9343(08)01121-2/abstract"Am J Med. 2009 Mar;122(3):222-9. Dobesh PP, Wittkowsky AK, Stacy Z et al. Key articles and guidelines for the prevention of venous thromboembolism. HYPERLINK "http://www.atypon-link.com/doi/abs/10.1592/phco.29.4.410"Pharmacotherapy. 2009 Apr;29(4):410-58. The ACTIVE Investigators. Effect of clopidogrel added to aspirin in patients with atrial fibrillation. HYPERLINK "http://content.nejm.org/cgi/content/abstract/NEJMoa0901301v1"N Engl J Med. 2009 Mar 31. Johnson JA, Boerwinkle E, Zineh I et al. Pharmacogenomics of antihypertensive drugs: Rationale and design of the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) study. HYPERLINK "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6W9H-4VGDNT2-4&_user=1069263&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000051270&_version=1&_urlVersion=0&_userid=1069263&md5=8b9931055c5a9b78f31409e3dc76ace0"Am Heart J. 2009 Mar;157(3):442-9. The following study and editorial comment are related: Chhatriwalla AK, Nicholls SJ, Wang TH et al. Low levels of low-density lipoprotein cholesterol and blood pressure and progression of coronary atherosclerosis. HYPERLINK "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T18-4VXB5C0-4&_user=1069263&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000051270&_version=1&_urlVersion=0&_userid=1069263&md5=2eb2d8ef7105628f906277d276887636" J Am Coll Cardiol. 2009 Mar 31;53(13):1110-5. Tobis JM, Perlowski A. Atheroma volume by intravascular ultrasound as a surrogate for clinical end points. HYPERLINK "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T18-4VXB5C0-5&_user=1069263&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000051270&_version=1&_urlVersion=0&_userid=1069263&md5=4e57136fe5ce5618be071014d7d21cba"J Am Coll Cardiol. 2009 Mar 31;53(13):1116-8. Glynn RJ, Danielson E, Fonseca FA et al. A randomized trial of rosuvastatin in the prevention of venous thromboembolism. HYPERLINK "http://content.nejm.org/cgi/content/abstract/NEJMoa0900241v1"N Engl J Med. 2009 Mar 29. The following study and comment are related: Teerlink JR, Metra M, Felker GM et al. Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): A multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study. HYPERLINK "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T1B-4VY0RFR-3&_user=1069263&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000051270&_version=1&_urlVersion=0&_userid=1069263&md5=108984d26c7e0e23ca7ddd51deac4bd0"Lancet. 2009 Mar 27. Hernandez AF, Granger CB. Advancing care for acute heart failure-no time to relax. HYPERLINK "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T1B-4VY0RFR-4&_user=1069263&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000051270&_version=1&_urlVersion=0&_userid=1069263&md5=5f3fddc9bba7b41ed4915e7b39f1b0b1"Lancet. 2009 Mar 27. The following study and editorial are related: Fellstrm BC, Jardine AG, Schmieder R et al. for the AURORA Study Group. Rosuvastatin and cardiovascular events in patients undergoing hemodialysis. HYPERLINK "http://content.nejm.org/cgi/content/abstract/360/14/1395"N Engl J Med. 2009 Mar 30. Strippoli GF, Craig JC. Sunset for statins after AURORA? HYPERLINK "http://content.nejm.org/cgi/content/extract/360/14/1455"N Engl J Med. 2009 Mar 30. Giugliano RP, White JA, Bode C, Armstrong PW et al. for the EARLY ACS Investigators. Early versus delayed, provisional eptifibatide in acute coronary syndromes. HYPERLINK "http://content.nejm.org/cgi/content/abstract/NEJMoa0901316v2"N Engl J Med. 2009 Mar 31. The following study and commentary are related: Juurlink DN, Gomes T, Ko DT et al. A population-based study of the drug interaction between proton pump inhibitors and clopidogrel. HYPERLINK "http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=19176635"CMAJ. 2009 Mar 31;180(7):713-8. Lau WC, Gurbel PA. The drug-drug interaction between proton pump inhibitors and clopidogrel. HYPERLINK "http://www.cmaj.ca/cgi/content/short/180/7/699"CMAJ. 2009 Mar 31;180(7):699-700. The following study and comment are related: Ridker PM, Danielson E, Fonseca FA et al. on behalf of the JUPITER Trial Study Group. Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: A prospective study of the JUPITER trial. HYPERLINK "http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=DetailsSearch&Term=19329177%5buid%5d"Lancet. 2009 Mar 27. [Epub ahead of print] Desprs JP. Bringing JUPITER down to earth. HYPERLINK "http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=DetailsSearch&Term=19329179%5buid%5d"Lancet. 2009 Mar 27. [Epub ahead of print] Yusuf S, Lonn E, Bosch J. Lipid lowering for primary prevention. HYPERLINK "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T1B-4W048P2-5&_user=1069263&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000051270&_version=1&_urlVersion=0&_userid=1069263&md5=e32fe08f264b242bb289bd03cef428e9"Lancet. 2009 Apr 4;373(9670):1152-5. Bergmann O, Bhardwaj RD, Bernard S et al. Evidence for cardiomyocyte renewal in humans. HYPERLINK "http://www.sciencemag.org/cgi/content/abstract/324/5923/98"Science. 2009 Apr 3;324(5923):98-102. The following two studies were published in the same issue of JAMA: O'Connor CM, Whellan DJ, Lee KL et al.for the HF-ACTION Investigators. Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial. HYPERLINK "http://jama.ama-assn.org/cgi/content/abstract/301/14/1439"JAMA. 2009 Apr 8;301(14):1439-50. Flynn KE, Pia IL, Whellan DJ et al. Effects of exercise training on health status in patients with chronic heart failure: HF-ACTION randomized controlled trial. HYPERLINK "http://jama.ama-assn.org/cgi/content/abstract/301/14/1451"JAMA. 2009 Apr 8;301(14):1451-9. Van der Niepen P, Woestenburg A, Bri H et al. Effectiveness of valsartan for treatment of hypertension: patient profiling and hierarchical modeling of determinants and outcomes (the PREVIEW Study)(May). HYPERLINK "http://www.theannals.com/cgi/content/abstract/aph.1L576v1"Ann Pharmacother. 2009 Apr 7. [Epub ahead of print] CAS-Related Meir B. HYPERLINK "http://www.nytimes.com/2009/03/27/business/27clinic.html"An overseer of trials in medicine draws fire. New York Times. March 27, 2009. DeAngelis CD. The Roman article: Read it again--in the same journal.  HYPERLINK "http://jama.ama-assn.org/cgi/content/extract/301/13/1382?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=deangelis&searchid=1&FIRSTINDEX=10&resourcetype=HWCIT" JAMA. 2009 Apr 1;301(13):1382-3. Hughes B. The comparative effectiveness challenge.  HYPERLINK "http://www.nature.com/doifinder/10.1038/nrd2866" Nat Rev Drug Discov. 2009 Apr;8(4):261-3. Rothman DJ, McDonald WJ, Berkowitz CD et al. Professional medical associations and their relationships with industry: A proposal for controlling conflict of interest. HYPERLINK "http://jama.ama-assn.org/cgi/content/abstract/301/13/1367"JAMA. 2009 Apr 1;301(13):1367-72. HYPERLINK "http://units.sla.org/division/dbio/publications/resources/dbio100.html"Top 100 journals in biology and medicine. Alexandria VA: Special Libraries Association Biomedical & Life Sciences Division; accessed March 30, 2009. Thompson CA. Supply of pharmacists in work force has improved, government says. HYPERLINK "http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=DetailsSearch&Term=19336827%5buid%5d"Am J Health Syst Pharm. 2009 Apr 15;66(8):701-2. Nathan JP, Gim S. Responding to drug information requests. HYPERLINK "http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=DetailsSearch&Term=responding%5bTitle%5d+AND+drug%5bTitle%5d+AND+information%5bTitle%5d+AND+requests%5bTitle%5d"Am J Health Syst Pharm. 2009 Apr 15;66(8):706-11. Citrome L, Ketter TA. Teaching the philosophy and tools of evidence-based medicine: Misunderstandings and solutions. HYPERLINK "http://www3.interscience.wiley.com/journal/121675845/abstract"Int J Clin Pract. 2009 Mar;63(3):353-9. Viereck C, Boudes P. An analysis of current pharmaceutical industry practices for making clinical trial results publicly accessible. HYPERLINK "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B7P72-4W0WJDC-1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=4f6e21deccfb4f4e8490bb3e18f4b802"Contemp Clin Trials. 2009 Apr 5. [Epub ahead of print]  Cerebrovascular Diseases Parsons MW, Miteff F, Bateman GA et al. Acute ischemic stroke: Imaging-guided tenecteplase treatment in an extended time window.  HYPERLINK "http://www.neurology.org/cgi/content/abstract/72/10/915" Neurology. 2009 Mar 10;72(10):915-21.  Uher R, Maier W, Hauser J, et al. Differential efficacy of escitalopram and nortriptyline on dimensional measures of depression. HYPERLINK "http://bjp.rcpsych.org/cgi/content/abstract/194/3/252"Br J Psychiatry. 2009 Mar;194(3):252-9. CNS Gellene D. HYPERLINK "http://www.latimes.com/features/health/la-he-sleep30-2009mar30,0,1418832.story"Sleeping pill use grows as economy keeps people up at night: More Americans are turning to such medications, but they're not without risks, such as dependence, next-day drowsiness, memory loss and sleep-walking.  Los Angeles Times. March 30, 2009. Rahimi R, Nikfar S, Abdollahi M. Efficacy and tolerability of Hypericum perforatum in major depressive disorder in comparison with selective serotonin reuptake inhibitors: A meta-analysis. HYPERLINK "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TBR-4TX33T4-2&_user=1069263&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000051270&_version=1&_urlVersion=0&_userid=1069263&md5=c73adecc44a9f8d27fdba7895b1940e7"Prog Neuropsychopharmacol Biol Psychiatry. 2009 Feb 1;33(1):118-27. Exley C, Swarbrick L, Gherardi RK, Authier FJ. A role for the body burden of aluminium in vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome. HYPERLINK "http://www.medical-hypotheses.com/article/S0306-9877(08)00493-3/abstract"Med Hypotheses. 2009 Feb;72(2):135-9. The following review and perspective are related: Citrome L. Olanzapine pamoate: A stick in time? A review of the efficacy and safety profile of a new depot formulation of a second-generation antipsychotic. HYPERLINK "http://www3.interscience.wiley.com/journal/121427935/abstract?CRETRY=1&SRETRY=0"Int J Clin Pract. 2009 Jan;63(1):140-50. Epub 2008 Oct 1. Taylor DM. Olanzapine pamoate - blockbuster or damp squib?  HYPERLINK "http://www3.interscience.wiley.com/journal/122264327/abstract" Int J Clin Pract. 2009 Apr;63(4):540-1. The following study and commentary are related: Simpson DM, Gracies JM, Yablon SA et al for BoNT/TZD Study Team. Botulinum neurotoxin versus tizanidine in upper limb spasticity: A placebo-controlled study. HYPERLINK "http://jnnp.bmj.com/cgi/content/abstract/80/4/380"J Neurol Neurosurg Psychiatry. 2009 Apr;80(4):380-5. Sheean G. Botulinum toxin should be first-line treatment for poststroke spasticity. HYPERLINK "http://jnnp.bmj.com/cgi/content/extract/80/4/359"J Neurol Neurosurg Psychiatry. 2009 Apr;80(4):359. van Geffen EC, Kruijtbosch M, Egberts AC et al. Patients' perceptions of information received at the start of selective serotonin-reuptake inhibitor treatment: Implications for community pharmacy. HYPERLINK "http://www.theannals.com/cgi/content/abstract/43/4/642"Ann Pharmacother. 2009 Apr;43(4):642-9. Epub 2009 Mar 24. McGorry PD. Is early intervention in the major psychiatric disorders justified? Yes. HYPERLINK "http://www.bmj.com/cgi/content/extract/337/aug04_1/a695"BMJ. 2008 Aug 4;337:a695. doi: 10.1136/bmj.a695. Pelosi A. Is early intervention in the major psychiatric disorders justified? No. HYPERLINK "http://www.bmj.com/cgi/content/extract/337/aug04_1/a710"BMJ. 2008 Aug 4;337:a710. doi: 10.1136/bmj.a710. Critical Care Lam SW, Eschenauer GA, Carver PL. Evolving role of early antifungals in the adult intensive care unit. HYPERLINK "http://ovidsp.tx.ovid.com/spb/ovidweb.cgi?WebLinkFrameset=1&S=NGLHFPCOMKDDOCABNCGLNDMLEKCDAA00&returnUrl=http%3a%2f%2fovidsp.tx.ovid.com%2fspb%2fovidweb.cgi%3fMain%2bSearch%2bPage%3d1%26S%3dNGLHFPCOMKDDOCABNCGLNDMLEKCDAA00&directlink=http%3a%2f%2fgraphics." Crit Care Med. 2009 Mar 25. [Epub ahead of print] Dermatology Koulouri O, Conway GS. Management of hirsutism. HYPERLINK "http://www.bmj.com/cgi/content/extract/338/mar27_1/b847"BMJ. 2009 Mar 27;338:b847.doi: 10.1136/bmj.b847. Saint Louis C. HYPERLINK "http://www.nytimes.com/2009/04/02/fashion/02SKIN.html"Heads up, Botux. New York Times. April 2, 2009. Diabetes Shah M, Chandalia M, Adams-Huet B et al. Effect of a high fiber diet compared to a moderate fiber diet on calcium and other mineral balance in subjects with type 2 diabetes mellitus. HYPERLINK "http://care.diabetesjournals.org/cgi/content/abstract/dc09-0126v1"Diabetes Care. 2009 Mar 11. [Epub ahead of print] Keating CL, Dixon JB, Moodie ML et al. Cost-efficacy of surgically induced weight loss for the management of type 2 diabetes: A randomized controlled trial. HYPERLINK "http://care.diabetesjournals.org/cgi/content/abstract/32/4/580"Diabetes Care. 2009 Apr;32(4):580-4. Epub 2009 Jan 26. HYPERLINK "http://effectivehealthcare.ahrq.gov/healthInfo.cfm?infotype=sg&ProcessID=18&DocID=125"Premixed insulin for type 2 diabetes: A guide for adults. Rockville MD: U.S. Agency for Healthcare Research and Quality (AHRQ); March 2009. HYPERLINK "http://effectivehealthcare.ahrq.gov/healthInfo.cfm?infotype=sg&ProcessID=18&DocID=124"Clinicians guide: Premixed insulin analogues: A comparison with other treatments for type 2 diabetes.  Rockville MD: U.S. Agency for Health care Research and Quality (AHRQ); March 2009. These two bedside to bench commentaries are related: Razani B, Semenkovich CF. Getting away from glucose: Stop sugarcoating diabetes. HYPERLINK "http://www.nature.com/nm/journal/v15/n4/abs/nm0409-372.html"Nat Med. 2009 Apr;15(4):372-3. Shoelson SE, Goldfine AB. Getting away from glucose: Fanning the flames of obesity-induced inflammation. HYPERLINK "http://www.nature.com/nm/journal/v15/n4/full/nm0409-373.html"Nat Med. 2009 Apr;15(4):373-4. Devore EE, Stampfer MJ, Breteler MM et al. Dietary fat intake and cognitive decline in women with type 2 diabetes. HYPERLINK "http://care.diabetesjournals.org/cgi/content/abstract/32/4/635?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1=devore&searchid=1&FIRSTINDEX=0&sortspec=relevance&firstpage=635&resourcetype=HWCIT"Diabetes Care. 2009 Apr;32(4):635-40. Keating CL, Dixon JB, Moodie ML et al. Cost-effectiveness of surgically induced weight loss for the management of type 2 diabetes: Modeled lifetime analysis. HYPERLINK "http://care.diabetesjournals.org/cgi/content/abstract/32/4/567?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1=keating&searchid=1&FIRSTINDEX=0&sortspec=relevance&firstpage=567&resourcetype=HWCIT"Diabetes Care. 2009 Apr;32(4):567-74. Epub 2009 Jan 26. Nettleton JA, Lutsey PL, Wang Y et al. Diet soda intake and risk of incident metabolic syndrome and type 2 diabetes in the Multi-Ethnic Study of Atherosclerosis (MESA). HYPERLINK "http://care.diabetesjournals.org/cgi/content/abstract/32/4/688?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1=nettleton&searchid=1&FIRSTINDEX=0&sortspec=relevance&firstpage=688&resourcetype=HWCIT"Diabetes Care. 2009 Apr;32(4):688-94. Epub 2009 Jan 16. Drug Compounding & Biopharmaceutics Canann D, Tyler LS, Barker B, Condie C. Visual compatibility of i.v. medications routinely used in bone marrow transplant recipients. HYPERLINK "http://www.ajhp.org/cgi/content/abstract/66/8/727"Am J Health Syst Pharm. 2009 Apr 15;66(8):727-9. The Indian Polycap Study (TIPS). Effects of a polypill (Polycap) on risk factors in middle-aged individuals without cardiovascular disease (TIPS): A phase II, double-blind, randomised trial. HYPERLINK "http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(09)60611-5/abstract"Lancet. 2009 Mar 30. [Epub ahead of print] Hill SW, Varker AS, Karlage K et al. Analysis of drug content and weight uniformity for half-tablets of 6 commonly split medications. HYPERLINK "http://www.amcp.org/data/jmcp/253-261.pdf"J Manag Care Pharm. 2009 Apr;15(3):253-61. Cannon CP. Can the polypill save the world from heart disease? HYPERLINK "http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(09)60652-8/fulltext"Lancet. 2009 Mar 30. Bawarski WE, Chidlowsky E, Bharali DJ, Mousa SA. Emerging nanopharmaceuticals.  HYPERLINK "http://www.nanomedjournal.com/article/S1549-9634(08)00084-1/abstract" Nanomedicine. 2008 Dec;4(4):273-82. Epub 2008 Jul 18. Review.  Wermeling DP. Intranasal delivery of antiepileptic medications for treatment of seizures. HYPERLINK "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B8G3D-4VY25N9-R&_user=1069263&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000051270&_version=1&_urlVersion=0&_userid=1069263&md5=85c095657e278b9bd740901c11c465c3"Neurotherapeutics. 2009 Apr;6(2):352-8. Bawarski WE, Chidlowsky E, Bharali DJ, Mousa SA. Emerging nanopharmaceuticals. HYPERLINK "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B7MDB-4T13JBK-3&_user=1069263&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000051270&_version=1&_urlVersion=0&_userid=1069263&md5=e85be2c0f00b20498d637824abda9056"Nanomedicine. 2008 Dec;4(4):273-82. Epub 2008 Jul 18. Review. Drug Safety HYPERLINK "http://www.consumerlab.com/news/Multivitamin_Multimineral_Test_Results/3_31_2009/"News: ConsumerLab.com warns of problems with multivitamins and vitamin water: Defects found in over 30% of supplements selected for testing; several popular children's multis exceed tolerable limits.  White Pains NY: ComsumerLab.com; March 31, 2009. HYPERLINK "http://www.fda.gov/Cder/aers/statistics/default.htm"Adverse Event Reporting System (AERS) Statistics as of December 31, 2008.  Rockville MD: US FDA; April 6, 2009. HYPERLINK "http://www.fda.gov/bbs/topics/NEWS/2009/NEW01992.html"FDA Statement on the voluntary withdrawal of Raptiva from the U.S. market.  Rockville MD: US FDA. April 8, 2009. HYPERLINK "http://www.fda.gov/bbs/topics/NEWS/2009/NEW01983.html"FDA acts to halt marketing of certain unapproved prescription narcotic drugs patients still have access to approved narcotics for pain relief.  FDA News. March 31, 2009. Moussally K, Oraichi D, Brard A. Herbal products use during pregnancy: Prevalence and predictors. HYPERLINK "http://www3.interscience.wiley.com/journal/122280705/abstract?CRETRY=1&SRETRY=0"Pharmacoepidemiol Drug Saf. 2009 Mar 26. [Epub ahead of print] Uetrecht J. Immune-mediated adverse drug reactions. HYPERLINK "http://pubs.acs.org/doi/abs/10.1021/tx800389u"Chem Res Toxicol. 2009 Jan;22(1):24-34. Review. Eichler HG, Abadie E, Raine JM, Salmonson T. Safe drugs and the cost of good intentions. HYPERLINK "http://content.nejm.org/cgi/content/extract/360/14/1378"N Engl J Med. 2009 Apr 2;360(14):1378-80. Blumentals WA, Harris ST, Cole RE et al. Risk of severe gastrointestinal events in women treated with monthly ibandronate or weekly alendronate and risedronate. HYPERLINK "http://www.theannals.com/cgi/content/abstract/43/4/577"Ann Pharmacother. 2009 Apr;43(4):577-85. Small MD, Barrett A, Price GM. The impact of computerized prescribing on error rate in a department of Oncology/Hematology. HYPERLINK "http://opp.sagepub.com/cgi/content/short/14/4/181"J Oncol Pharm Pract. 2008 Dec;14(4):181-7. Cahoon L. The curious case of clioquinol. HYPERLINK "http://www.nature.com/nm/journal/v15/n4/abs/nm0409-356.html"Nat Med. 2009 Apr;15(4):356-9. [No authors listed]. Risky business. HYPERLINK "http://www.nature.com/nm/journal/v15/n4/abs/nm0409-345.html"Nat Med. 2009 Apr;15(4):345. Loke YK, Jeevanantham V, Singh S. Bisphosphonates and atrial fibrillation: Systematic review and meta-analysis. HYPERLINK "http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=DetailsSearch&Term=19338379%5buid%5d+AND+(%222009%22%5bPDAT%5d+%3A+%223000%22%5bPDAT%5d)"Drug Saf. 2009;32(3):219-28. Grande LA, Mendez RD, Krug RT, Verschuyl EJ. Attention--grapefruit! HYPERLINK "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T1B-4W048P2-13&_user=1069263&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000051270&_version=1&_urlVersion=0&_userid=1069263&md5=b947013233a7a233c7896a6170e02aec"Lancet. 2009 Apr 4;373(9670):1222. Wong IC, Wong LY, Cranswick NE. Minimising medication errors in children. HYPERLINK "http://adc.bmj.com/cgi/content/abstract/94/2/161?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1=wong&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&firstpage=161&resourcetype=HWCIT"Arch Dis Child. 2009 Feb;94(2):161-4. Epub 2008 Oct 1. Fong DS, Contreras R. Glitazone use associated with diabetic macular edema. HYPERLINK "http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=DetailsSearch&Term=19181303%5Buid%5D"Am J Ophthalmol. 2009 Apr;147(4):583-586.e1. Epub 2009 Feb 1. Hachem C, Morgan R, Johnson M et al. Statins and the risk of colorectal carcinoma: A nested case-control study in veterans with diabetes. HYPERLINK "http://www.nature.com/ajg/journal/vaop/ncurrent/abs/ajg200964a.html"Am J Gastroenterol. 2009 Apr 7. [Epub ahead of print] Bostwick JM, Hecksel KA, Stevens SR et al. Frequency of new-onset pathologic compulsive gambling or hypersexuality after drug treatment of idiopathic Parkinson disease. HYPERLINK "http://www.mayoclinicproceedings.com/content/84/4/310.abstract"Mayo Clin Proc. 2009 Apr;84(4):310-6. Emergency Medicine Doyon S, Klein-Schwartz W. Hepatotoxicity despite early administration of intravenous N-acetylcysteine for acute acetaminophen overdose. HYPERLINK "http://www3.interscience.wiley.com/journal/121507725/abstract?CRETRY=1&SRETRY=0"Acad Emerg Med.2009 Jan;16(1):34-9. Environmental Concerns Schier JG, Wolkin AF, Valentin-Blasini L et al. Perchlorate exposure from infant formula and comparisons with the perchlorate reference dose. HYPERLINK "http://www.nature.com/jes/journal/vaop/ncurrent/abs/jes200918a.html"J Expo Sci Environ Epidemiol. 2009 Mar 18. [Epub ahead of print].  Ramirez AJ, Brain RA, Usenko S et al. Occurrence of pharmaceuticals and personal care products (PPCPs) in fish: Results of a national pilot study in the U.S. HYPERLINK "http://www.epa.gov/waterscience/ppcp/studies/fish-tissue.html"Environ Toxicol Chem. 2009 Mar 25:1. Madden JC, Enoch SJ, Hewitt M, Cronin MT. Pharmaceuticals in the environment: Good practice in predicting acute ecotoxicological effects. HYPERLINK "http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=DetailsSearch&Term=19118609%5Buid%5D"Toxicol Lett. 2009 Mar 10;185(2):85-101. Epub 2008 Dec 9. Eye Disorders Ali TK, El-Remessy AB. Diabetic retinopathy: Current management and experimental therapeutic targets. HYPERLINK "http://www.atypon-link.com/doi/abs/10.1592/phco.29.2.182"Pharmacotherapy. 2009 Feb;29(2):182-92. Review. Gastrointestinal Diseases The following study and commentary are related: Schnitzler F, Fidder H, Ferrante M et al. Long-term outcome of treatment with infliximab in 614 patients with Crohn's disease: Results from a single-centre cohort. HYPERLINK "http://gut.bmj.com/cgi/content/abstract/58/4/492"Gut. 2009 Apr;58(4):492-500. Schlmerich J. Balancing the risks and benefits of prolonged use of infliximab. HYPERLINK "http://gut.bmj.com/cgi/content/extract/58/4/477"Gut. 2009 Apr;58(4):477-8. Ford AC, Talley NJ, Schoenfeld PS et al. Efficacy of antidepressants and psychological therapies in irritable bowel syndrome: Systematic review and meta-analysis. HYPERLINK "http://gut.bmj.com/cgi/content/short/58/3/367"Gut. 2009 Mar;58(3):367-78. Review. Sung JJ, Barkun A, Kuipers EJ et al. Intravenous esomeprazole for prevention of recurrent peptic ulcer bleeding: A randomized trial. HYPERLINK "http://www.annals.org/cgi/content/full/150/7/455"Ann Intern Med. 2009 Apr 7;150(7):455-64. Epub 2009 Feb 16. Infectious Diseases Theuretzbacher U. Future antibiotics scenarios: Is the tide starting to turn? HYPERLINK "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T7H-4VYW68P-4&_user=1069263&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000051270&_version=1&_urlVersion=0&_userid=1069263&md5=f1969aaf668f4f83aee77b414f8abb0d"Int J Antimicrob Agents. 2009 Mar 31. The following article and editorial are related: Kitahata MM, Gange SJ, Abraham AG et al. for the NA-ACCORD Investigators. Effect of early versus deferred antiretroviral therapy for HIV on survival. HYPERLINK "http://content.nejm.org/cgi/content/abstract/NEJMoa0807252v1"N Engl J Med. 2009 Apr 1. Sax PE, Baden LR. When to start antiretroviral therapy -- Ready when you are? HYPERLINK "http://content.nejm.org/cgi/content/extract/NEJMe0902713v1"N Engl J Med. 2009 Apr 1. Mens Health Foreman J. HYPERLINK "http://www.latimes.com/features/health/la-he-testosterone30-2009mar30,0,6596296.column"Testosterone replacement and prostate cancer: Is therapy safe?; For men with low testosterone, taking supplements can mean greater libido, energy and muscle. It also goes against decades of medical thinking.  Los Angeles Times. March 30, 2009. Yan L, Spitznagel EL. Soy consumption and prostate cancer risk in men: A revisit of a meta-analysis. HYPERLINK "http://www.ajcn.org/cgi/content/full/89/4/1155"Am J Clin Nutr. 2009 Apr;89(4):1155-63. News Canada Mittelstaedt M. HYPERLINK "http://www.theglobeandmail.com/servlet/story/RTGAM.20090403.wlvitamind03/BNStory/specialScienceandHealth/home"Researchers who touted high vitamin D doses shut out of panel. Globe and Mail. April 3, 2009. News US Hirsch J. HYPERLINK "http://www.chicagotribune.com/business/yourmoney/sns-yourmoney-0405medicines,0,3084109.story"Options abound for cutting prescription costs. Chicagotribune.com. April 5, 2009. Silva C. HYPERLINK "http://www.ama-assn.org/amednews/2009/04/06/gvsb0406.htm"Medicare Advantage defenders decry proposed cuts: Many physicians say proposed funding cuts to the private plans are long overdue, but supporters fear cuts could cause disruptions in care.  Amednews.com. April 6, 2009. Willis G. HYPERLINK "http://money.cnn.com/2009/04/03/pf/saving/free_health_care_willis/index.htm?section=money_latest"Freebies for the out-of-work: Free health care, free job training, Gerri Willis provides helpful tips if you find yourself unemployed.  CNNMoney.com. April 3, 2009. HYPERLINK "http://news.moneycentral.msn.com/provider/providerarticle.aspx?feed=AP&date=20090406&id=9763558"CVS-Google Health pact now includes drugstores. BusinessWeek.com. April 6, 2009. Associated Press. HYPERLINK "http://archives.chicagotribune.com/2009/apr/06/health/chi-ap-il-birthcontrol"Ill. cant force dispensing morning-after pill.  Chicagotribune.com. April 6, 2009. Jack A. HYPERLINK "http://www.ft.com/cms/s/0/5d0bf864-21f7-11de-8380-00144feabdc0.html"Pharmas lack science expertise at the top.  Ft.com. April 5, 2009. Adams JU. HYPERLINK "http://www.latimes.com/features/health/la-he-closer6-2009apr06,0,2767554.story"Teens and the morning after pill: A judge's ruling means girls under 17 may soon have over-the-counter access to the emergency contraceptive.  Los Angeles Times. April 6, 2009. Larkin C. HYPERLINK "http://www.bloomberg.com/apps/news?pid=20601087&sid=aIlA1ULcXPxo&refer=home"Drugmakers cited by FDA for misleading Internet ads (Update 1).  Bloomberg.com. April 3, 2009. Harris G. HYPERLINK "http://www.nytimes.com/2009/03/27/health/policy/27drug.html"Bill would let copycats compete with biotech drugs.  New York Times. March 27, 2009. Lunzer Kritz F. HYPERLINK "http://www.latimes.com/features/health/la-he-yourmoney30-2009mar30,0,913087.story"Get help paying for drugs: Drug makers step up with adi as strapped consumers cut health spending in tough times.  Los Angeles Times. March 30, 2009. Okie S. A to-do list for the new FDA Commissioner. HYPERLINK "http://content.nejm.org/cgi/content/extract/360/14/1373"N Engl J Med. 2009 Mar 14. Brooks J. US grapples with solutions to preventable medical errors. HYPERLINK "http://www.cmaj.ca/cgi/content/full/180/7/E4"CMAJ. 2009 Mar 31;180(7):E4-5. Loeppke R, Taitel M, Haufle V et al. Health and productivity as a business strategy: A multiemployer studyHYPERLINK "http://www.ncbi.nlm.nih.gov/pubmed/19339899?dopt=Abstract". J Occup Environ Med. 2009 Mar 31. [Epub ahead of print] Obesity, Weight Loss & Eating Disorders HYPERLINK "http://www.oma.org/media/news/pr090407-a.asp"Media release: Ontarios doctors call for calorie labeling on fast food and cafeteria menus.  Toronto ON: Ontario Medical Association; April 7, 2009. Klump KL, Bulik CM, Kaye WH et al. Academy for eating disorders position paper: Eating disorders are serious mental illnesses. HYPERLINK "http://www3.interscience.wiley.com/journal/121483347/abstract?CRETRY=1&SRETRY=0"Int J Eat Disord. 2009 Mar;42(2):97-103. Harris KC, Kuramoto LK, Schulzer M, Retallack JE. Effect of school-based physical activity interventions on body mass index in children: A meta-analysis. HYPERLINK "http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=19332753"CMAJ. 2009 Mar 31;180(7):719-26. Baur LA. Tackling the epidemic of childhood obesity. HYPERLINK "http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=19332745"CMAJ. 2009 Mar31;180(7):701-2. Pollack A. HYPERLINK "http://www.nytimes.com/2009/03/31/business/31obese.html"Obesity drug clears trial, Arena says. New York Times. March 31, 2009. Whitlock EP, OConnor EA, Williams SB et al. HYPERLINK "http://www.ahrq.gov/clinic/tp/chwghttp.htm" \l "Report"Effectiveness of weight management programs in children and adolescents.  Evidence Report/Technology Assessment No. 170 (Prepared by the Oregon Evidence-based Practice Center under Contract No. 290-02-0024). AHRQ Publication No. 08-E014. Rockville MD: Agency for Healthcare Research and Quality. September 2008. McPartland JM. Obesity, the endocannabinoid system, and bias arising from pharmaceutical sponsorship. HYPERLINK "http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=19333392"PLoS ONE. 2009;4(3):e5092. Fox CB, Treadway AK, Blaszczyk AT, Sleeper RB. Megestrol acetate and mirtazapine for the treatment of unplanned weight loss in the elderly. HYPERLINK "http://www.atypon-link.com/PPI/doi/abs/10.1592/phco.29.4.383"Pharmacotherapy. 2009 Apr;29(4):383-97. Obstetrics and Gynecology McCowan LM, Dekker GA, Chan E et al.for the SCOPE consortium. Spontaneous preterm birth and small for gestational age infants in women who stop smoking early in pregnancy: Prospective cohort study.HYPERLINK "http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=19325177" BMJ. 2009 Mar 26;338:b1081. Edenborough FP, Borgo G, Knoop C et al. for the European Cystic Fibrosis Society. Guidelines for the management of pregnancy in women with cystic fibrosis. HYPERLINK "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6X2D-4R5G3DG-1&_user=1069263&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000051270&_version=1&_urlVersion=0&_userid=1069263&md5=8654eebddc338057abc2376541c37c5c"J Cyst Fibros. 2008 Jan;7 Suppl 1:S2-32. Oncology Huijbers EJ, Baars JW, Schutte PF et al. Propofol extravasation in a breast cancer patient. HYPERLINK "http://opp.sagepub.com/cgi/content/short/14/4/195"J Oncol Pharm Pract. 2008 Dec;14(4):195-8. Epub 2008 Aug 27. Nehring R. Trial watch: Pivotal oncology trials: Outlook for Q2 2009.  HYPERLINK "http://www.nature.com/doifinder/10.1038/nrd2861" Nat Rev Drug Discov. 2009 Apr;8(4):266. Parkin DM, Olsen AH, Sasieni P. The potential for prevention of colorectal cancer in the UK. HYPERLINK "http://ovidsp.tx.ovid.com/spa/ovidweb.cgi?QS2=434f4e1a73d37e8c7d142c752735f503686f689007a398c5eaa44fdb9daf5e9b7bcfa53a68084813e3d631daa9bebc4e435f00d58372064193f253fe6bfb97761d343991e27cce58659bb303068cc968c28d7bae08804fbc0543ca68019a5b5061aa46fa7292ab9bdd"Eur J Cancer Prev. 2009 Feb 20. Satia JA, Littman A, Slatore CG et al. Long-term use of beta-carotene, retinol, lycopene, and lutein supplements and lung cancer risk: Results from the VITamins And Lifestyle (VITAL) study. HYPERLINK "http://aje.oxfordjournals.org/cgi/content/short/169/7/815"Am J Epidemiol. 2009 Apr 1;169(7):815-28. Spencer A, Prince HM, Roberts AW et al. Consolidation therapy with low-dose thalidomide and prednisolone prolongs the survival of multiple myeloma patients undergoing a single autologous stem-cell transplantation procedure. HYPERLINK "http://jco.ascopubs.org/cgi/content/short/27/11/1788"J Clin Oncol. 2009 Mar 9. The following study and editorial are related: Islami F, Pourshams A, Nasrollahzadeh D et al. Tea drinking habits and oesophageal cancer in a high risk area in northern Iran: Population based case-control study. HYPERLINK "http://www.bmj.com/cgi/content/abstract/338/mar26_2/b929"BMJ. 2009 Mar 26;338:b929. doi: 10.1136/bmj.b929. Whiteman DC. Hot tea and increased risk of oesophageal cancer. HYPERLINK "http://www.bmj.com/cgi/content/extract/338/mar26_2/b610"BMJ. 2009 Mar 26;338:b610. doi: 10.1136/bmj.b610. OTCs, Nutrition, NHPs, Life Style Topics, etc. Kolata G. HYPERLINK "http://www.nytimes.com/2009/03/26/health/nutrition/26best.html"Its time to make a coffee run. New York Times. March 26, 2009. Hutchinson A. HYPERLINK "http://www.theglobeandmail.com/servlet/story/RTGAM.20090327.wljockology27/BNStory/specialScienceandHealth/home"Supplements prove to be no magic bullets.  Globe and Mail. March 27, 2009. Beck L. HYPERLINK "http://www.theglobeandmail.com/servlet/story/RTGAM.20090408.wlbeck08art1832/BNStory/specialScienceandHealth/home"Breathe easier by eating right: A Mediterranean diet provides the vitamins, minerals and antioxidants needed for a healthy set of lungs.  Globe and Mail. April 8, 2009. Pain & Palliative Care Santaguida PL, Gross A, Busse J et al. HYPERLINK "http://www.ahrq.gov/Clinic/tp/backcamtp.htm" \l "Report"Evidence report on complementary and alternative medicine in back pain utilization report.  Evidence Report/Technology Assessment No. 177. (Prepared by the McMaster University Evidence-based Practice Center, under Contract No. 290-02-0020.) AHRQ Publication No.09-E006. Rockville MD: Agency for Healthcare Research and Quality; February 2009. Kim L, Lipton S, Deodhar A. Pregabalin for fibromyalgia: Some relief but no cure. HYPERLINK "http://www.ccjm.org/content/76/4/255.long"Cleve Clin J Med. 2009 Apr;76(4):255-61. Mllmann H, Nef HM, Hamm CW, Elssser A. How to manage patients with need for antiplatelet therapy in the setting of (un-)planned surgery. HYPERLINK "http://www.springerlink.com/content/j4n6727kx60ut164/" Clin Res Cardiol. 2009 Jan;98(1):8-15. Epub 2008 Oct 13. Review. The following study and editorial are related: Dworkin RH, Barbano RL, Tyring SK et al. A randomized, placebo-controlled trial of oxycodone and of gabapentin for acute pain in herpes zoster. HYPERLINK "http://www.painjournalonline.com/article/S0304-3959(08)00761-6/abstract"Pain. 2009 Apr;142(3):209-17. Haanp M. Controlled release oxycodone - an evidence-based treatment for pain in acute herpes zoster. HYPERLINK "http://www.painjournalonline.com/article/S0304-3959(09)00061-X/abstract"Pain. 2009 Apr;142(3):175-6. Cunningham JL, Rome JD, Kerkvliet JL, Townsend CO. Reduction in medication costs for patients with chronic nonmalignant pain completing a pain rehabilitation program: A prospective analysis of admission, discharge, and 6-month follow-up medication costs. HYPERLINK "http://www.ncbi.nlm.nih.gov/pubmed/19302437?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum"Pain Med. 2009 Mar 19. Taddio A, Yiu A, Smith RW et al. Variability in clinical practice guidelines for sweetening agents in newborn infants undergoing painful procedures. HYPERLINK "http://journals.lww.com/clinicalpain/Abstract/2009/02000/Variability_in_Clinical_Practice_Guidelines_for.12.aspx"Clin J Pain. 2009 Feb;25(2):153-5. The following study and editorial are related: Erstad BL, Puntillo K, Gilbert HC et al. Pain management principles in the critically ill. HYPERLINK "http://www.chestjournal.org/content/135/4/1075.abstract"Chest. 2009 Apr;135(4):1075-86. Sessler CN. Progress toward eliminating inadequately managed pain in the ICU through interdisciplinary care. HYPERLINK "http://www.chestjournal.org/content/135/4/894.citation"Chest. 2009 Apr;135(4):894-6. Parasitic Diseases Goddard J, deShazo R. Bed bugs (Cimex lectularius) and clinical consequences of their bites. HYPERLINK "http://jama.ama-assn.org/cgi/content/short/301/13/1358"JAMA. 2009 Apr 1;301(13):1358-66. Review. Hildreth CJ, Burke AE, Glass RM. JAMA patient page. Bed bugs.  HYPERLINK "http://jama.ama-assn.org/cgi/content/full/301/13/1398" JAMA. 2009 Apr 1;301(13):1398. HYPERLINK "http://www.fda.gov/bbs/topics/NEWS/2009/NEW01993.html"FDA approves benzyl alcohol lotion for the treatment of head lice.  FDA News. April 9, 2009. Chen L, Appel LJ, Loria C et al. Reduction in consumption of sugar-sweetened beverages is associated with weight loss: The PREMIER trial. HYPERLINK "http://www.ajcn.org/cgi/content/abstract/ajcn.2008.27240v1"Am J Clin Nutr. 2009 Apr 1. Pediatrics Robson WL. Clinical practice. Evaluation and management of enuresis. HYPERLINK "http://content.nejm.org/cgi/content/extract/360/14/1429"N Engl J Med. 2009 Apr 2;360(14):1429-36. Review. Williams SB, O'Connor EA, Eder M, Whitlock EP. Screening for child and adolescent depression in primary care settings: A systematic evidence review for the US Preventive Services Task Force. HYPERLINK "http://pediatrics.aappublications.org/cgi/content/abstract/123/4/e716"Pediatrics. 2009 Apr;123(4):e716-35. Taveras EM, Rifas-Shiman SL, Belfort MB et al. Weight status in the first 6 months of life and obesity at 3 years of age. HYPERLINK "http://pediatrics.aappublications.org/cgi/content/full/123/4/1177"Pediatrics. 2009 Apr;123(4):1177-83. Marra F, Marra CA, Richardson K, Lynd LD et al. Antibiotic use in children is associated with increased risk of asthma. HYPERLINK "http://pediatrics.aappublications.org/cgi/content/abstract/123/3/1003"Pediatrics. 2009 Mar;123(3):1003-10. Tal R, Voelzke BB, Land S et al. Vasculogenic erectile dysfunction in teenagers: A 5-year multi-institutional experienceHYPERLINK "http://www3.interscience.wiley.com/journal/121483049/abstract". BJU Int. 2009 Mar;103(5):646-50. Muckelbauer R, Libuda L, Clausen K et al. Promotion and provision of drinking water in schools for overweight prevention: Randomized, controlled cluster trial. HYPERLINK "http://pediatrics.aappublications.org/cgi/content/full/123/4/e661"Pediatrics. 2009 Apr;123(4):e661-7. Mukattash TL, Millership JS, Collier PS, McElnay JC. Public awareness and views on unlicensed use of medicines in children. HYPERLINK "http://www3.interscience.wiley.com/journal/121391795/abstract"Br J Clin Pharmacol. 2008 Dec;66(6):838-45. US Preventive Services Task Force. Screening and treatment for major depressive disorder in children and adolescents: US Preventive Services Task Force recommendation statement. HYPERLINK "http://pediatrics.aappublications.org/cgi/content/abstract/123/4/1223"Pediatrics. 2009 Apr;123(4):1223-8. Liberman JN, Berger JE, Lewis M. Prevalence of antihypertensive, antidiabetic, and dyslipidemic prescription medication use among children and adolescents. HYPERLINK "http://archpedi.ama-assn.org/cgi/content/short/163/4/357"Arch Pediatr Adolesc Med. 2009 Apr;163(4):357-64. Van Meter DJ, Corriveau M, Ahern JW, Lahiri T. A survey of once-daily dosage tobramycin therapy in patients with cystic fibrosis. HYPERLINK "http://www3.interscience.wiley.com/journal/122265974/abstract"Pediatr Pulmonol. 2009Apr;44(4):325-9. The following study and editorial are related: Liberman JN, Berger JE, Lewis M. Prevalence of antihypertensive, antidiabetic, and dyslipidemic prescription medication use among children and adolescents. HYPERLINK "http://archpedi.ama-assn.org/cgi/content/abstract/163/4/357"Arch Pediatr Adolesc Med. 2009 Apr;163(4):357-64. Daniels SR. Use of pharmacologic agents for treatment of diabetes mellitus, dyslipidemia, and hypertension in children and adolescents. HYPERLINK "http://archpedi.ama-assn.org/cgi/content/full/163/4/389"Arch Pediatr Adolesc Med. 2009 Apr;163(4):389-91. Gogia S, Sachdev HS. Neonatal vitamin A supplementation for prevention of mortality and morbidity in infancy: Systematic review of randomised controlled trials. HYPERLINK "http://www.bmj.com/cgi/content/abstract/338/mar27_1/b919"BMJ. 2009 Mar 27;338:b919. doi: 10.1136/bmj.b919. Pharmacogenetics & Genetics Davis JC, Furstenthal L, Desai AA et al. The microeconomics of personalized medicine: Today's challenge and tomorrow's promise. HYPERLINK "http://www.nature.com/nrd/journal/v8/n4/abs/nrd2825.html"Nat Rev Drug Discov. 2009 Apr;8(4):279-86. Caulfield T, Fullerton SM, Ali-Khan SE et al. Race and ancestry in biomedical research: exploring the challenges. HYPERLINK "http://www.genomemedicine.com/content/1/1/8/abstract/"Genome Med. 2009 Jan 21;1(1):8. [Epub ahead of print] Respiratory Tract Diseases Walters JA, Gibson PG, Wood-Baker R et al. Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease. HYPERLINK "http://mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD001288/frame.html"Cochrane Database Syst Rev. 2009 Jan 21;(1):CD001288. Review. Clark MJ, Million RP. Allergic rhinitis: Market evolution. HYPERLINK "http://www.nature.com/doifinder/10.1038/nrd2762"Nat Rev Drug Discov. 2009 pr;8(4):271-2. Rheumatology Fitzcharles MA, DaCosta D, Ware MA, Shir Y. Patient barriers to pain management may contribute to poor pain control in rheumatoid arthritis. HYPERLINK "http://www.jpain.org/article/S1526-5900(08)00797-9/abstract"J Pain.2009 Mar;10(3):300-5. Adams JU. New relief for gout. HYPERLINK "http://www.nature.com/nbt/journal/v27/n4/abs/nbt0409-309.html"Nat Biotechnol. 2009 Apr;27(4):309-11. Socioeconomic Topics Belluck P. HYPERLINK "http://www.nytimes.com/2009/04/09/health/09stress.html"Recession anxiety steps into everyday lives.  New York Times. April 9, 2009. Alkhateeb FM, Khanfar NM, Clauson KA. Characteristics of physicians who frequently see pharmaceutical sales representatives. HYPERLINK "http://pdfserve.informaworld.com/536880_770885140_907343483.pdf"J Hosp Mark Public Relations. 2009 Jan-Jun;19(1):2-14. Pindolia VK, Stebelsky L, Romain TM et al. Mitigation of medication mishaps via medication therapy management. HYPERLINK "http://www.theannals.com/cgi/content/abstract/43/4/611"Ann Pharmacother. 2009 Apr;43(4):611-20. Gostin LO, Nass S. Reforming the HIPAA Privacy Rule: Safeguarding privacy and promoting research. HYPERLINK "http://jama.ama-assn.org/cgi/content/short/301/13/1373"JAMA. 2009 Apr 1;301(13):1373-5. Pellegrino AN, Martin MT, Tilton JJ, Touchette DR. Medication therapy management services: Definitions and outcomes. HYPERLINK "http://www.ingentaconnect.com/content/adis/dgs/2009/00000069/00000004/art00001?token=00471283b47b76504c48763f2550233e6c78736a59386a332b254362544f6d4e227aeee"Drugs. 2009;69(4):393-406. Smith F. The quality of private pharmacy services in low and middle-income countries: A systematic review. HYPERLINK "http://www.springerlink.com/content/452255374043701j/"Pharm World Sci. 2009 Apr 3. Jencks SF, Williams MV, Coleman EA. Rehospitalizations among patients in the Medicare fee-for-service program. HYPERLINK "http://content.nejm.org/cgi/content/abstract/360/14/1418"N Engl J Med. 2009 Apr 2;360(14):1418-28. The following article and comment are related: Garattini S, Chalmers I. Patients and the public deserve big changes in evaluation of drugs. HYPERLINK "http://www.bmj.com/cgi/content/extract/338/mar31_3/b1025"BMJ. 2009 Mar 31;338:b1025. Tremblay M. Commentary: Risks of doing as the Romans do. HYPERLINK "http://www.bmj.com/cgi/content/extract/338/mar31_3/b1107"BMJ. 2009 Mar31;338:b1107. Clauson KA, Khanfar NM, Polen HH, Gibson F. Nurse prescribers' interactions with and perceptions of pharmaceutical sales representatives. HYPERLINK "http://www3.interscience.wiley.com/journal/121562111/abstract"J Clin Nurs. 2009 Jan;18(2):228-33. Naik AD, Woofter AL, Skinner JM, Abraham NS. Pharmaceutical company influence on nonsteroidal anti-inflammatory drug prescribing behaviors. HYPERLINK "http://www.ajmc.com/web-exclusives/managed-care/AJMC_09Apr_Naik_Exclusiv_e9toe15"Am J Manag Care.2009 Apr 1;15(4):e9-e15. Ellitt GR, Brien JA, Aslani P, Chen TF. Quality patient care and pharmacists' role in its continuity: A systematic review. HYPERLINK "http://www.theannals.com/cgi/content/abstract/43/4/677"Ann Pharmacother. 2009 Apr;43(4):677-91. Astrand B, Montelius E, Petersson G, Ekedahl A. Assessment of ePrescription quality: An observational study at three mail-order pharmacies. HYPERLINK "http://www.biomedcentral.com/1472-6947/9/8/abstract/"BMC Med Inform Decis Mak. 2009 Jan 26;9:8. Millar J, McNamee P, Heaney D et al. Does a system of instalment dispensing for newly prescribed medicines save NHS costs? Results from a feasibility study. HYPERLINK "http://fampra.oxfordjournals.org/cgi/content/abstract/26/2/163"Fam Pract. 2009 Apr;26(2):163-8. Epub 2009 Jan 6. Nietert PJ, Tilley BC, Zhao W et al. Two pharmacy interventions to improve refill persistence for chronic disease medications: A randomized, controlled trial. HYPERLINK "http://www.ncbi.nlm.nih.gov/pubmed/19106728"Med Care. 2009 Jan;47(1):32-40. Chen PW. HYPERLINK "http://www.nytimes.com/2009/04/02/health/02chen.html"Do you know what your doctor is talking about?  New York Times. April 2, 2009. Williams A. HYPERLINK "http://www.nytimes.com/2009/04/05/business/05vitamins.html"As economy is down, vitamin sales are up.  New York Times. April 5, 2009. Carpenter S. HYPERLINK "http://www.nytimes.com/2009/03/31/health/31sick.html?partner=rss&emc=rss"Treating an illness is one thing, what about a patient with many?  New York Times. March 31, 2009. Stats and Facts HYPERLINK "http://www.meps.ahrq.gov/mepsweb/data_stats/tables_compendia_hh_interactive.jsp?_SERVICE=MEPSSocket0&_PROGRAM=MEPSPGM.TC.SAS&File=HCFY2006&Table=HCFY2006%5FCNDXP%5FC&_Debug="Medical expenditure panel survey. Table 3: Total expenses for selected conditions by type of service: United States, 2006 expenses are reported in millions. Rockville MD: U.S. Agency for Healthcare Research and Quality; date published? (Amounts spent on prescribed medicines for more than five dozen conditions are listed.) Keyhani S, Federman A. Fact or fiction: The need for independent pharmaceutical policy research. HYPERLINK "http://www.springerlink.com/content/705712473521uwt2/"J Gen Intern Med. 2009 Apr 3. Zhang Y, Adams AS, Ross-Degnan D et al. Effects of prior authorization on medication discontinuation among Medicaid beneficiaries with bipolar disorder. HYPERLINK "http://proquest.umi.com/pqdlink?Ver=1&Exp=04-08-2014&FMT=7&DID=1674153601&RQT=309&clientId=15814&cfc=1"Psychiatr Serv. 2009 Apr;60(4):520-7. HYPERLINK "http://www.imshealthcanada.com/web/end/0,3150,77303623_63872702_84335036,00.html"Press release: IMS Health reports retail prescription volume grew 7.1 percent in 2008: Generics prescriptions primary driver of growth.  Montreal QC: IMS Canada; March 26, 2009. (. . . includes link to seven tables HYPERLINK "http://www.imshealthcanada.com/vgn/images/portal/CIT_40000873/49/44/84335049IMSCanadaChartsENGLISH.pdf". . . detailing 2008 Canadian pharmaceutical market performance. HYPERLINK "http://www.nanosresearch.com/library/polls/POLNAT-W09-T364.pdf"National issues of concern: What is your most important national issue of concern [Unprompted].  Toronto ON: NANOS Research; March 28, 2009. Kaiser Commission on Medicaid facts. HYPERLINK "http://www.kff.org/medicaid/7872.cfm"Medicaid and the uninsured: American Recovery and Reinvestment Act (AARA): Medicaid and health care provisions.  Publication #7872. Washington DC: Henry J. Kaiser Family Foundation; March 2009. HYPERLINK "http://www.healthgrades.com/media/dms/pdf/PatientSafetyInAmericanHospitalsStudy2009.pdf"The sixth annual HealthGrades patient safety in American hospitals study.  Healthgrades. April 2009. Substance Use & Substance-Related Disorders Van Zee A. The promotion and marketing of oxycontin: Commercial triumph, public health tragedy. HYPERLINK "http://www.ajph.org/cgi/content/abstract/99/2/221"Am J Public Health. 2009 Feb;99(2):221-7. Ruiz-Veguilla M, Gurpegui M, Barrign ML et al. Fewer neurological soft signs among first episode psychosis patients with heavy cannabis use. HYPERLINK "http://www.ncbi.nlm.nih.gov/pubmed/18805673"Schizophr Res. 2009 Feb;107(2-3):158-64. Gilbertson R, Ceballos NA, Prather R, Nixon SJ. Effects of acute alcohol consumption in older and younger adults: Perceived impairment versus psychomotor performance. HYPERLINK "http://www.jsad.com/jsad/volumes"J Stud Alcohol Drugs. 2009 Mar;70(2):242-52. Spiller H, Lorenz DJ. Trends in volatile substance abuse. HYPERLINK "http://www.ncbi.nlm.nih.gov/pubmed/19340679?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum"J Addict Dis. 2009;28(2):164-70. Pooler D, Sheheen F, Davidson J. Professional impairment: A history and one state's response. HYPERLINK "http://www.ncbi.nlm.nih.gov/pubmed/19340673?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum"J Addict Dis. 2009;28(2):113-23. Clark S. Formulating an effective response to emergency room drug diversion by drug seeking patientsHYPERLINK "http://www.ncbi.nlm.nih.gov/pubmed/19323241?ordinalpos=10&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum". J Healthc Prot Manage. 2009;25(1):1-8. Moore D, Aveyard P, Connock M et al. Effectiveness and safety of nicotine replacement therapy assisted reduction to stop smoking: Systematic review and meta-analysis. HYPERLINK "http://www.bmj.com/cgi/content/abstract/338/apr02_3/b1024"BMJ. 2009 Apr 2;338:b1024. doi: 10.1136/bmj.b1024. Wallack T. HYPERLINK "http://www.boston.com/business/healthcare/articles/2009/03/23/alcoholism_drug_not_an_easy_sell/"Alcoholism drug not an easy sell: Despite praise, local biotech finds barriers.  Boston.com. March 23, 2009. HYPERLINK "https://www.bcma.org/improving-addiction-care-british-columbia"Stepping forward: Improving addiction care in British Columbia. A policy paper by BCs physicians. Vancouver BC: Brtish Columbia Medical Association; March 2009. The following four items on smoking cessation are all related: Steinberg MB, Greenhaus S, Schmelzer AC et al. Triple-combination pharmacotherapy for medically ill smokers: A randomized trial. HYPERLINK "http://www.annals.org/cgi/content/full/150/7/447"Ann Intern Med. 2009 Apr 7;150(7):447-54. Ellerbeck EF, Mahnken JD, Cupertino AP et al. Effect of varying levels of disease management on smoking cessation: A randomized trial. HYPERLINK "http://www.annals.org/cgi/content/full/150/7/437"Ann Intern Med. 2009 Apr 7;150(7):437-46. Rigotti NA. The future of tobacco treatment in the health care system. HYPERLINK "http://www.annals.org/cgi/content/full/150/7/496"Ann Intern Med. 2009 Apr 7;150(7):496-7. [No authors listed]. Summaries for patients. Comparison of 3 strategies to quit smoking. HYPERLINK "http://www.annals.org/cgi/content/full/150/7/I-36"Ann Intern Med. 2009 Apr 7;150(7):I-36. King A, Cao D, Vanier C, Wilcox T. Naltrexone decreases heavy drinking rates in smoking cessation treatment: An exploratory study. HYPERLINK "http://www3.interscience.wiley.com/journal/122268276/abstract"Alcohol Clin Exp Res. 2009 Mar 19. [Epub ahead of print] Fitzgerald N, Watson H, McCaig D, Stewart D. Developing and evaluating training for community pharmacists to deliver interventions on alcohol issues. HYPERLINK "http://www.springerlink.com/content/033235l81172871h/"Pharm World Sci. 2009 Apr;31(2):149-53. Epub 2009 Feb 7. Surgery, Transplantation, Anesthesiology & Perioperative Care Maynard G, O'Malley CW, Kirsh SR. Perioperative care of the geriatric patient with diabetes or hyperglycemia. HYPERLINK "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B75HP-4TW17C0-9&_user=1069263&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000051270&_version=1&_urlVersion=0&_userid=1069263&md5=8b6a2ca13810e41f454c7fe2fbfa442a"Clin Geriatr Med. 2008 Nov;24(4):649-65, viii. Review. Womens Health Col NF, Fairfield KM, Ewan-Whyte C, Miller H. In the clinic. Menopause. HYPERLINK "http://www.annals.org/cgi/reprint/150/7/ITC4-1.pdf"Ann Intern Med. 2009 Apr 7;150(7):ITC4-1-15; quiz ITC4-16,. By & About Faculty, Students, Alumni and Friends Sketris IS, Langille Ingram EM, Lummis HL. Strategic opportunities for effective optimal prescribing and medication management. HYPERLINK "http://www.cjcp.ca/hm/?id=723"Can J Clin Pharmacol. 2009 Winter;16(1):e103-25. Epub 2009 Jan 30. The End Until Next Time!!!      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